Pharmaceutical Engineering

Wednesday AM

PHAR1R St-Fran

Process Analytical Technologies (PAT)

Organizer(s) - Nicolas Abatzoglou
Chair(s) - Jean-Sebastien Simard and Mahmoud Mirmehrabi

10:00 00396 Process analytical technologies in the pharmaceutical industry and the role of chemical engineering Levins J.
10:40 00397 Development of a NIR quantitative model to evaluate segregation in a hopper before the compression step of a simple pharmaceutical formulation Abatzoglou N., Cartilier L., Cournoyer A., Simard J.-S.
11:00 00398 Qualitative and quantitative blend homogeneity determination of a multicomponent dry pharmaceutical formulation for direct compression using near-infrared spectroscopy in a V-type blender Lapointe-Garant P.P., Abatzoglou N., Simard J.-S.
11:20 00399 Cohesive multicomponent dense powder flow characterization of a pharmaceutical dry formulation for direct compression using Near-Infrared Spectroscopy as a PAT tool Benedetti C., Abatzoglou N., Simard J.-S.
11:40 00400 Rheological properties of pharmaceutical powders Léonard G., Abatzoglou N., Simard J.-S.
12:00 End of Session

Wednesday PM

PHAR2R St-Fran

Pharmaceutical Processes

Organizer(s) - Nicolas Abatzoglou
Chair(s) - François Bertrand and Jamal Chaouki

13:40 00466 Determination of macroscopic mixing properties of granular materials from particle tracking experiments Doucet J., Chaouki J., Bertrand F.
14:00 00467 Design-oriented research for process understanding and optimization of divided solids mixing in pharmaceutical processes Abatzoglou N., Simard J.-S.
14:20 00468 Mixing effects in crystallization operations in the pharmaceutical industry Paul E.L.
14:40 00469 Quantitative, solubility and molecular structure analysis of buspirone hydrochloride polymorphs (anti-anxiety drug) Sheikhzadeh M., Rohani S., Jutan A., Murthy K., Horne S.
15:00 00470 Thermodynamics insight into pharmaceuticals hydrates: a case study Mirmehrabi M., Tadayon S., Yu Q., Deshmukh S.
15:20 Coffee Break
15:40 00471 Modeling of granular mixing dynamics using Markov chains and the discrete element method Doucet J., Hudon N., Bertrand F., Chaouki J.
16:00 00472 Development and evaluation of a prediction model for granule properties in a high shear wet granulation (HSWG) process Dasgupta D., Debnath S., Thibert R.
16:20 00473 Comparative study of cohesionless granular mixing in bin- and V-blenders Lemieux M., Gosselin P., Chaouki J., Bertrand F.
16:40 00474 Development of a chitosan nanoparticle carrier for the anticancer prodrug cladribine Domaratzki R.E., Ghanem A.
17:00 End of Session

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